Antimicrobial Efficacy of Nano-Based ICM on E.F
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-60
SponsorTanta University
About this trial
This in-vivo study aims to evaluate the antimicrobial effect of nano based intracanal medications (Triple antibiotic-loaded chitosan nanoparticles and chlorohexidine loaded by silver nanoparticles) on Enterococcus faecalis count reduction in secondary endodontic infection cases.
Eligibility criteria
Qualifiers
Single rooted, single canal premolar teeth.
Teeth indicated for non-surgical root canal retreatment.
Teeth have signs and/or symptoms of post-treatment disease manifested by recurrent acute and/or chronic periapical abscess.
Teeth have clinical signs and symptoms of endodontic failure as sensitivity to percussion, pain, swelling or fistula.
Disqualifiers
Patients with any systemic diseases.
Pregnant or lactating patients.
Immunocompromised patients.
Non-restorable tooth.
Trial design
Treatments tested in this trial
- antimicrobial efficacy of nano based intracanal medications on Enterococcus faecalis count reduction in secondary endodontic infection cases.
Treatment groups
30 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov