Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich Fibrin
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age10-80
SponsorUniversity of Bari Aldo Moro
About this trial
Autogenous tooth transplantation (autotransplantation) represents a biologically valid alternative to implant therapy, particularly in young patients where implant placement is contraindicated due to ongoing skeletal growth. This approach preserves alveolar bone volume, maintains periodontal proprioception, and allows physiological adaptation over time.
Eligibility criteria
Qualifiers
Early loss of permanent teeth due to trauma, extensive caries, or agenesis.
Dental agenesis, particularly involving premolars or incisors, when a suitable donor tooth is available.
Replacement of non-restorable teeth (fractures or destructive caries).
Preservation of alveolar bone in growing patients where implant therapy is contraindicated.
Disqualifiers
Poor patient compliance.
Active infection at the recipient site.
Smoking of more than 15 cigarettes a day
Pregnancy or breastfeeding at date of inclusion
Trial design
Treatments tested in this trial
- Autogenous Tooth Transplantation
- Alveolar Prf graft
Treatment groups
5 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov