Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRush University Medical Center

About this trial

For patients requiring mechanical ventilation, spontaneous breathing trials (SBTs) are conducted to determine if it is safe to remove the breathing tube. There are multiple methods for conducting SBTs. The purpose of this study is to compare the effects of 2 methods, pressure support ventilation (PSV) versus automatic tube compensation (ATC), on successful extubation for critically ill adult patients who received mechanical ventilation for over 24 hours.

Eligibility criteria

Qualifiers

Admitted to intensive care unit (ICU)

Age 18 years or older

Requiring invasive mechanical ventilation for at least 24 hours

Pass spontaneous breathing trial screen criteria

Disqualifiers

Clinical decision made not to proceed with extubation regardless of spontaneous breathing trial (SBT) results

Do not intubate (DNI) order

Presence of tracheostomy

Pregnancy

Trial design

Treatments tested in this trial

  • Pressure Support Ventilation (PSV)
  • Automatic tube compensation (ATC)

Treatment groups

880 Participants
are divided into 4 treatment groups

Sponsors and collaborators