Spontaneous Breathing Trial in ICU

3

Review clinical trials related to Spontaneous Breathing Trial in ICU. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Adults

For patients requiring mechanical ventilation, spontaneous breathing trials (SBTs) are conducted to determine if it is safe to remove the breathing tube. There are multiple methods for conducting SBTs. The purpose of this study is to compare the effects of 2 methods, pressure support ventilation (PSV) versus automatic tube compensation (ATC), on successful extubation for critically ill adult patients who received mechanical ventilation for over 24 hours.

Participants needed: 880
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Rush University Medical CenterUpdated: Jul 2, 2026Locations: 1
Eligibility criteria

Admitted to intensive care unit (ICU) [+3]

Clinical decision made not to proceed with extubation regardless of spontaneous... [+6]

Status: Recruiting

Effectiveness of Pet-Robotic Intervention in Intensive Care Unit Patients

This study aims to develop a novel nursing intervention involving robotic pet companionship to reduce anxiety in patients undergoing spontaneous breathing trials.

Participants needed: 24
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: National Taiwan University HospitalUpdated: Sep 9, 2025Locations: 1
Eligibility criteria

Aged 18 years or older with clear consciousness. [+2]

Multidrug-resistant organism infection. [+6]

Status: Not yet recruiting

Benefits of Immersive Virtual Reality on Dyspnoea During a Weaning Test in the Intensive Care Unit.

A weaning trial is a test that simulates physiological respiratory conditions after extubation in order to assess the patient's ability to breathe without the assistance of a ventilator. This test is highly susceptible to induce dyspnea, with 62% of patients reporting a dyspnea score on VAS greater than 3. Similarly, the prevalence of anxiety is high during weaning trials. 60% of patients treated in a respiratory weaning unit report psychological symptoms. Dyspnea can be a traumatic experience for patients. In intensive care, up to half of patients suffer from dyspnea, which is described by patients as one of the worst memories of their stay in intensive care. The virtual reality headset is a device that simulates a realistic, three-dimensional environment, allowing the patient to be totally immersed, so that they feel as if they are really present in a virtual world. This environment can be combined with hypnotic verbal support. The research hypothesis is that virtual reality during a spontaneous breathing trial would relieve the respiratory discomfort induced by the weaning trial. The secondary hypotheses are that virtual reality could reduce the anxiety associated with spontaneous breathing trials. These benefits could be associated to a reduction in ventilatory drive. To assess dyspnea a VAS scale will be used, as the MV-RDOS scale, and the amplitude of EMG activity of inspiratory muscles.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assistance Publique - Hôpitaux de ParisUpdated: Jul 3, 2025
Eligibility criteria

Age ≥ 18 years [+7]

Non french speaker [+8]