Avocado and Postprandial Responses

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-65
SponsorUniversity of Vermont Medical Center

About this trial

The purpose of this study is to see how adding avocado to a breakfast meal affects blood sugar control and signals of hunger and fullness after eating.

The investigators will test the effects of 3 breakfast meals on blood sugar control and signals of hunger and fullness after eating:

1. Whole-wheat bread and strawberry jam 2. Whole-wheat bread, strawberry jam, and avocado 3. Whole-wheat bread and strawberry jam (meal enriched with fat and fiber to mimic that of an avocado)

Participants will undergo 3 test periods, each separated by a week. Each test period consists of one day with set meals that the investigators will provide (breakfast, lunch, and dinner), and then the next morning, participants will eat a breakfast meal and have blood drawn several times over 4 hours.

Eligibility criteria

Qualifiers

Biological sex males or females

Age 21 to 65 years

BMI between 18.5 and 34.9 kg/m2

Disqualifiers

Actively pregnant or lactating women

Diagnosis of prediabetes or diabetes (fasting glucose >100 mg/dL)

Current diagnosis of uncontrolled hypertension (systolic BP: >160 mmHg, diastolic BP: >95 mmHg), may receive treatment for hypertension as long as on a stable regimen for the previous one month

Current diagnosis of uncontrolled hyperlipidemia (fasting total blood cholesterol >200 mg/dL, fasting triglycerides >200 mg/dL), may receive treatment for hyperlipidemia as long as on a stable regimen for the previous one month

Trial design

Treatments tested in this trial

  • Negative control
  • Avocado
  • Fat and fiber addition

Treatment groups

30 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University of Vermont Medical Center

Lead sponsor

Avocado Nutrition Center

Collaborator