Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorXuanwu Hospital, Beijing
About this trial
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.
Eligibility criteria
Qualifiers
Age ≥18 years, men or women.
Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA/MRA/DSA.
Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days.
Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.
Disqualifiers
Subjects with occlusions in both anterior and posterior circulation.
CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed).
Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset/last known well time, or missing major treatment information including whether EVT was performed).
Baseline NIHSS score <6.
Trial design
Treatments tested in this trial
- Endovascular Therapy
Treatment groups
518 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov