Large Core Infarct

3

Review clinical trials related to Large Core Infarct. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct

This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.

Participants needed: 518
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Xuanwu Hospital, BeijingUpdated: Jan 20, 2026Locations: 1
Eligibility criteria

Age ≥18 years, men or women. [+3]

Subjects with occlusions in both anterior and posterior circulation. [+6]

Status: Recruiting

EVT in Acute Basilar Artery Occlusion With Large Infarction Core

A multicenter, prospective, open-label, blinded endpoint, randomized controlled trial designed to evaluate the efficacy and safety of best medical management (BMM) combined with endovascular treatment (EVT) versus BMM alone in acute basilar artery occlusion (BAO) patients with large infarct cores.

Participants needed: 348
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: The First Affiliated Hospital of Hainan Medical UniversityUpdated: Jul 29, 2025Locations: 1
Eligibility criteria

1. Age ≥18 years. 2. Symptoms and signs consistent with basilar artery ischemia....

1. Pre-stroke modified Rankin Scale (mRS) score >2. 2. Factors in the target ves...

Status: Not yet recruiting

Basilar Artery Occlusion Chinese Endovascular Trial in Patients With Large Core Infarct

This study evaluates the safety and efficacy of endovascular therapy for acute basilar artery occlusion with large core infarcts in a multicenter randomized trial.

Participants needed: 314
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Capital Medical UniversityUpdated: Jul 1, 2025Locations: 1
Eligibility criteria

Posterior circulation acute ischemic stroke within 24 hours from symptom onset/l... [+6]

Known hemorrhagic diathesis, coagulation factor deficiency, or oral anticoagulan... [+21]