Behavioral and Neural Representations of Subjective Effort Cost

ConditionFatigue
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorHugo W. Moser Research Institute at Kennedy Krieger, Inc.

About this trial

The goal of this proposal is to understand the common and distinct behavioral and neural representations of subjective effort valuation, and how these representations are influenced by fatigue and changes in motivation. It is hypothesized that the brain will use overlapping and distinct neural circuits to represent cognitive and physical effort value, and that fatigue and enhanced motivation will influence the subjective value of effort.

Eligibility criteria

Qualifiers

Right-handed

Age between 18 and 35 years old - Male or female

Any ethnicity

Disqualifiers

Neurological problems such as stroke, head injury, epilepsy, seizures, brain tumors, brain surgery, Parkinson's Disease (self- report)

Diagnosed history of severe psychiatric disease such as depression, schizophrenia (self-report)

Metal in the head or eyes

If they are pregnant or suspect that you may be pregnant

Trial design

Treatments tested in this trial

  • Cognitive Fatigue
  • Physical Fatigue
  • Rewarding Stimuli

Treatment groups

185 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator