Beverage Hydration Index of Different Solutions
ConditionHydration
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Memphis
About this trial
In this study, the impact of two electrolyte hydration stick products (Hydramin containing an electrolyte/amino acid formulation and an identical electrolyte product with the amino-acids replaced with carbohydrate, dextrose) dissolved in 1 liter of water will be assessed and compared to a control (1 liter Smart Water). It is hypothesized that the addition of amino acids and glycine should improve the Beverage Hydration Index above water alone and perform comparably to the carbohydrate rich solution.
This study will focus on general population (not athletes) and follow very similar approaches used in previous studies within the Center for Nutraceutical and Dietary Supplements Research, with the addition of blood glucose testing and body water measurements. Hydration will be assessed via fluid balance (the difference between the amount of water consumed and passed as urine) and calculations of beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water)as well as time in positive fluid balance, and specific gravity, and sodium and potassium in urine. Blood glucose before and following consumption using finger pricks and a glucometer will also be assessed.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Be age 18 years or older
male or female
have a body mass index (BMI)between 18.5-35 kg/m2 (not morbidly obese)
Be engaged in moderate physical activity, defined as ≤5 hours/week of aerobic exercise
Disqualifiers
None
Trial design
Design model
Crossover
Treatments tested in this trial
Hydramin hydration solution
Dietary supplement4 sticks of electrolyte and amino acid powder dissolved in 1 L Smart Water. Ingredients: Sodium, Chloride, Potassium, Magnesium, Vitamin C, AminoAbsorb (L-glutamine, L-Alanine, Glycine)
Carbohydrate and Electrolyte hydration solution
Dietary supplement4 sticks of electrolyte and carbohydrate powder dissolved in 1 L Smart Water. Ingredients: Sodium, Chloride, Potassium, Magnesium, Vitamin C, Dextrose
Water
Dietary supplement1 L Smart Water
Treatment groups
30 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Group A: Hydramin, Electrolyte and Carbohydrate, WaterExperimental treatment 3 interventions
Group B: Hydramin, Water, Electrolyte and CarbohydrateExperimental treatment 3 interventions
Group C: Electrolyte and Carbohydrate, Hydramin, WaterExperimental treatment 3 interventions
Group D: Electrolyte and Carbohydrate, Water, HydraminExperimental treatment 3 interventions
Group E: Water, Hydramin, Electrolyte and CarbohydrateExperimental treatment 3 interventions
Group F: Water, Electrolyte and Carbohydrate, HydraminExperimental treatment 3 interventions
Trial outcomes
Primary outcomes
1
Beverage Hydration Index
Beverage Hydration Index calculated as mass of urine collected following control (water) divided by the mass of urine collected following treatment
Time frame
0 minutes after beverage consumption2
Beverage Hydration Index
Beverage Hydration Index calculated as mass of urine collected following control (water) divided by the mass of urine collected following treatment
Time frame
60 minutes after beverage consumption3
Beverage Hydration Index
Beverage Hydration Index calculated as mass of urine collected following control (water) divided by the mass of urine collected following treatment
Time frame
120 minutes after beverage consumption4
Beverage Hydration Index
Beverage Hydration Index calculated as mass of urine collected following control (water) divided by the mass of urine collected following treatment
Time frame
180 minutes after beverage consumptionSecondary outcomes
1
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme) where higher scores for positive mood attributes indicating a better outcome and higher scores for both negative mood attributes and digestive traits generally indicating a worse outcome.
Time frame
0 minutes before beverage consumption2
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme) where higher scores for positive mood attributes indicating a better outcome and higher scores for both negative mood attributes and digestive traits generally indicating a worse outcome.
Time frame
0 minutes after beverage consumption3
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme) where higher scores for positive mood attributes indicating a better outcome and higher scores for both negative mood attributes and digestive traits generally indicating a worse outcome.
Time frame
60 minutes after beverage consumption4
Mood and Digestive Questionnaire
Subjects will be asked to self-assess their mood and digestive state via a visual analog scale questionnaire with scale 0 (None) to 10 (Extreme) where higher scores for positive mood attributes indicating a better outcome and higher scores for both negative mood attributes and digestive traits generally indicating a worse outcome.scale questionnaire with scale 0 (None) to 10 (Extreme) where higher scores for positive mood attributes being better outcome and higher scores for both negative mood attributes and digestive traits being worse.scale questionnaire with scale 0 (None) to 10 (Extreme)
Time frame
120 minutes after beverage consumptionSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Memphis
Lead sponsor
PharmaLinea Ltd.
Collaborator
Source ClinicalTrials.gov