Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorRush University Medical Center

About this trial

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are

* if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests

Participants will undergo

* cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH

Eligibility criteria

Qualifiers

Primary Intracerebral Hemorrhage

Age ≥ 18 and < 80 years

Disqualifiers

Pre-existing dementia

Trial design

Treatments tested in this trial

  • MRI
  • Blood Draw
  • Cognitive Test

Treatment groups

No treatment groups listed

Sponsors and collaborators

Rush University Medical Center

Lead sponsor

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborator