About this trial
The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are
* if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests
Participants will undergo
* cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH
Eligibility criteria
Qualifiers
Primary Intracerebral Hemorrhage
Age ≥ 18 and < 80 years
Disqualifiers
Pre-existing dementia
Trial design
Treatments tested in this trial
- MRI
- Blood Draw
- Cognitive Test
Treatment groups
Sponsors and collaborators
Rush University Medical Center
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator