Primary Intracerebral Hemorrhage

2

Review clinical trials related to Primary Intracerebral Hemorrhage. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH

Participants needed: 118
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Rush University Medical CenterUpdated: Jul 13, 2026Locations: 1Duration: 12 Months
Eligibility criteria

Primary Intracerebral Hemorrhage [+1]

Pre-existing dementia

Status: Recruiting

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

The goal of this clinical trial is to see if silent brain infarcts (SBIs), or stroke-like symptoms detectable during brain imaging, are a possible contributor to cognitive decline for patients diagnosed with spontaneous intracerebral hemorrhage (sICH), or blood clot in the brain. The main questions it aims to answer are * if SBIs in sICH are associated with a lower cognitive level and more rapid cognitive decline * if SBIs in sICH are associated with certain findings on brain imaging * if SBIs in sICH are associated with higher inflammation measured by certain blood tests Participants will undergo * cognitive testing during hospitalization, and at 3, 6 and 12 months after the sICH * Magnetic Resonance Imaging (MRI) of the brain during hospitalization and 12 months after the sICH * blood draws during hospitalization and at 3, 6 and 12 months after the sICH

Participants needed: 118
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Rush University Medical CenterUpdated: Aug 8, 2025Locations: 1Duration: 12 Months
Eligibility criteria

Primary Intracerebral Hemorrhage [+1]

ICH score > 2 [+3]