Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Aarhus

About this trial

The goal of this clinical trial is to gain insights into the effects of Blood Flow Restriction Exercise (BFRE) in patients with an acute Achilles tendon Rupture. The main questions it aims to answer are:

Is BFRE an effective adjunct to usual care when compared with only usual care? When is the optimal timing for initiating BFRE: In the early treatment stage or at the later stage after hospital treatment? Participants will receive an intervention comprising 12 weeks of BFRE as an adjunct to usual care.

* Either in the initial 1-12 weeks after Achilles tendon rupture, or * In the following 13-24 weeks after Achilles tendon rupture

Researchers will compare the two groups at 13 weeks (3 months) to compare BFRE to usual care, and at 25 weeks (6 months) to compare the two time points for initiating BFRE (early vs. late).

Eligibility criteria

Qualifiers

aged 18 years or older

have started initial treatment within 72 hours of Achilles tendon rupture

understand written and spoken Danish

Disqualifiers

bilateral Achilles tendon rupture

previous Achilles tendon rupture in either leg

decreased lower extremity function, caused by conditions other than Achilles tendon rupture

treated with fluoroquinolones within the last six months

Trial design

Treatments tested in this trial

  • Early exercise with partial Blood Flow Restriction
  • Late exercise with partial Blood Flow Restriction

Treatment groups

218 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Aarhus

Lead sponsor

Aarhus University Hospital

Collaborator

Aalborg University Hospital

Collaborator

Gødstrup Hospital

Collaborator

Regionshospitalet Horsens

Collaborator