About this trial
The goal of this clinical trial is to gain insights into the effects of Blood Flow Restriction Exercise (BFRE) in patients with an acute Achilles tendon Rupture. The main questions it aims to answer are:
Is BFRE an effective adjunct to usual care when compared with only usual care? When is the optimal timing for initiating BFRE: In the early treatment stage or at the later stage after hospital treatment? Participants will receive an intervention comprising 12 weeks of BFRE as an adjunct to usual care.
* Either in the initial 1-12 weeks after Achilles tendon rupture, or * In the following 13-24 weeks after Achilles tendon rupture
Researchers will compare the two groups at 13 weeks (3 months) to compare BFRE to usual care, and at 25 weeks (6 months) to compare the two time points for initiating BFRE (early vs. late).
Eligibility criteria
Qualifiers
aged 18 years or older
have started initial treatment within 72 hours of Achilles tendon rupture
understand written and spoken Danish
Disqualifiers
bilateral Achilles tendon rupture
previous Achilles tendon rupture in either leg
decreased lower extremity function, caused by conditions other than Achilles tendon rupture
treated with fluoroquinolones within the last six months
Trial design
Treatments tested in this trial
- Early exercise with partial Blood Flow Restriction
- Late exercise with partial Blood Flow Restriction
Treatment groups
Sponsors and collaborators
University of Aarhus
Lead sponsor
Aarhus University Hospital
Collaborator
Aalborg University Hospital
Collaborator
Gødstrup Hospital
Collaborator
Regionshospitalet Horsens
Collaborator