Cabergoline & Letrozole Versus Letrozole in Ovulation Induction in PCOS
ConditionPCOS
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorMst.Sumyara Khatun
About this trial
Does combined Cabergoline and letrozole increase ovulation rate What medical problems do participants have when taking drug Cabergoline and Letrozole ? Researchers will compare drug combination of Cabergoline and letrozole to letrozole alone to see combined cabergoline and letrozole works better as ovulation induction.
Participants will:
experimental group will receive Cabergoline and Letrozole comparator group will receive letrozole alone TVS Monitoring will be done for 3 cycle for ovarian response
Eligibility criteria
Qualifiers
PCOS patients diagnosed according to Rotterdam criteria.
Age: 18-35 years.
Primary or secondary subfertility.
Selected for ovulation induction.
Disqualifiers
Women suffered from PCOS like symptom ex. Late onset congenital adrenal hyperplasia, Cushing syndrome.
Serum prolactin (more than 50 ng/ml) (Kyritsi et al., 2018).
Male factor infertility.
Women with other infertility factors (endometriosis, PID,uterine & tubal causes of infertility).
Trial design
Treatments tested in this trial
- Letrozole 0.5mg
- Cabergoline 0.5 mg
Treatment groups
72 Participants
are divided into 2 treatment groupsSponsors and collaborators
Mst.Sumyara Khatun
Lead sponsor
Bangladesh Medical University
Sponsor institution
Bangladesh Medical University
Collaborator
Source ClinicalTrials.gov