Characterising the Network-Specific Effects of Piriform Cortex Stimulation Via SEEG

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age14-65
SponsorXuanwu Hospital, Beijing

About this trial

The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy. Using multimodal data, it seeks to link stimulation-evoked electrophysiological responses across brain networks with clinical outcomes, to inform targeted neuromodulation therapies.

Eligibility criteria

Qualifiers

The patients were diagnosed with drug-resistant epilepsy.

The patients underwent stereoelectroencephalography (SEEG) implantation for pre-surgical evaluation of epilepsy, with at least one electrode target reaching the piriform cortex

Participants/parents/legal guardian provide informed consent for inclusion

Disqualifiers

Subjects that experience surgical complications during the implant procedure will be excluded from the study

Trial design

Treatments tested in this trial

  • SEEG recordings and SPES

Treatment groups

10 Participants
are divided into 1 treatment group

Sponsors and collaborators