About this trial
The prospective study aims to characterize the network-specific modulatory effects of piriform cortex stimulation in patients undergoing stereotactic EEG for drug-resistant epilepsy. Using multimodal data, it seeks to link stimulation-evoked electrophysiological responses across brain networks with clinical outcomes, to inform targeted neuromodulation therapies.
Eligibility criteria
Qualifiers
The patients were diagnosed with drug-resistant epilepsy.
The patients underwent stereoelectroencephalography (SEEG) implantation for pre-surgical evaluation of epilepsy, with at least one electrode target reaching the piriform cortex
Participants/parents/legal guardian provide informed consent for inclusion
Disqualifiers
Subjects that experience surgical complications during the implant procedure will be excluded from the study
Trial design
Treatments tested in this trial
- SEEG recordings and SPES