Chlorhexidine Caps for CLABSI Prevention in Hemodialysis: a Pilot Randomized Controlled Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe University of Queensland

About this trial

The goal of this clinical trial is to compare a chlorhexidine antimicrobial barrier cap in patients requiring hemodialysis treatment to the standard hemodialysis caps currently used within the Metro North Kidney Health Service.

The main questions to answer are:

* Study Feasibility * Occurrence of infectious complications related to renal central venous catheters

Participants will be randomly allocated to receive either of the below hemodialysis caps to cover their hemodialysis catheter hub:

* The standard hemodialysis cap used at the Royal Brisbane and Women's Hospital, or * The intervention hemodialysis cap containing chlorhexidine inside it

Researchers will compare standard and chlorhexidine hemodialysis caps to see if the presence of chlorhexidine improves the occurrance of infectious complications related to the hemodialysis catheter.

Eligibility criteria

Qualifiers

Age≥18

Able to provide informed consent

Kidney failure requiring a tunnelled CVC for treatment (haemodialysis)

21 days BSI free

Disqualifiers

Current CLABSI

Known allergic to chlorhexidine and/or nylon and/or polypropylene.

Patients on an end-of-life pathway

People with a cognitive impairment and/or intellectual disability

Trial design

Treatments tested in this trial

  • ClearGuard HD
  • B Braun Combi-stopper

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

The University of Queensland

Lead sponsor

Royal Brisbane and Women's Hospital

Collaborator