This study will examine how removal of part or all of the pancreas affects blood sugar control, metabolism, and clinical outcomes over time.
The study will include adults with diabetes before surgery who undergo pancreatic surgery as part of routine clinical care at Fondazione Policlinico Universitario A. Gemelli IRCCS.
Researchers will study whether glycemic control worsens after surgery and whether this risk changes according to the type of pancreatic resection. The study will also examine changes in glucose metabolism, and cancer-related outcomes.
Information from routine clinical care, metabolic tests, imaging, and pancreatic tissue samples collected during surgery may be used for research analyses.
Adult patients (≥18 years)
Diabetes mellitus at baseline
Undergoing partial, near-total, or total pancreatectomy at the study center for benign or malignant pancreatic disease
Availability of clinical and metabolic follow-up data according to study component
Age <18 years
Absence of diabetes mellitus at baseline
Missing essential clinical data or incomplete follow-up precluding evaluation of study outcomes
Severe pre-existing non-oncologic clinical conditions with life expectancy <6 months
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead sponsor
European Foundation for the Study of Diabetes
Collaborator