About this trial
The aim of the study is to compare the caries-preventive effect of the test and control toothpaste in order to proof the non-inferiority of the test toothpaste compared to the control.
Eligibility criteria
Qualifiers
A minimum of 10 healthy molars and premolars (DMFS of these teeth = 0)
Willingness to use an electric (powered) toothbrush
Willingness to use interdental floss
Willingness to have bitewing radiographs taken
Disqualifiers
Untreated caries [clinical investigation and analysis with an intraoral camera (DIAGNOcam)] (→ unsuitable subjects with one or two untreated caries in need of a restoration can become eligible after restorative therapy. If there are three or more untreated caries patients will be excluded)
Xerostomia (medication, radiation, disease induced)
Chemo/radiation therapy
Physical or mental disability which prevents proper oral health care
Trial design
Treatments tested in this trial
- 2% Calcium Hypophosphite Toothpaste
- Sodium Fluoride Toothpaste (1450 ppm F)
Treatment groups
Sponsors and collaborators
Dr. Joachim Enax
Lead sponsor
Dr. Kurt Wolff GmbH & Co. KG
Sponsor institution
Department of Integrated Dentistry Medical University of Białystok
Collaborator
Poznan University of Medical Sciences, Department of Integrated Dentistry
Collaborator