Caries, Dental

7

Review clinical trials related to Caries, Dental. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparative Study of Caries-Preventive Effects: 2% Calcium Hypophosphite Toothpaste vs. Sodium Fluoride Toothpaste (1450ppm F)

The aim of the study is to compare the caries-preventive effect of the test and control toothpaste in order to proof the non-inferiority of the test toothpaste compared to the control.

Participants needed: 164
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Dr. Joachim EnaxUpdated: Apr 13, 2026Locations: 2
Eligibility criteria

A minimum of 10 healthy molars and premolars (DMFS of these teeth = 0) [+4]

Untreated caries [clinical investigation and analysis with an intraoral camera (... [+10]

Status: Recruiting

Effect of AI-Supported Child-Friendly Communication on Dental Anxiety in Pediatric Patients

This study compares the effects of traditional behavior management techniques and AI-assisted child-friendly communication on dental anxiety, physiological stress, and pain perception during local anesthesia in healthy children aged 6-12. The aim is to evaluate the effectiveness of AI-supported communication tools in reducing anxiety and improving comfort in pediatric dental treatments, potentially enhancing clinical outcomes and advancing technology use in pediatric dentistry.

Participants needed: 60
Trial details
Age: 7-12Biological sex: AllType: InterventionalSponsor: Çanakkale Onsekiz Mart UniversityUpdated: Dec 24, 2025Locations: 1
Eligibility criteria

Children volunteers and their parents/legal guardians who have read and signed t... [+4]

Children volunteers and their parents/legal guardians who read the informed cons... [+4]

Status: Not yet recruiting

3D-printed Ceromer Crowns Versus Stainless Steel in Posterior Primary Molars

The aim of the study is to compare preformed metal crowns and 3D-printed ceromer crowns in primary molars of 4-9 years old children. The main questions it aims to answer are: * How does 3D-printed ceromer crowns compare clincally to stainless steel crowns when restoring posterior molars? * What is the level of satisfaction of the patient with both materials? * What is the level of parental satisfaction with both materials? Study methodology: This study is a split-mouth clinical trial where participants will receive at least one of each materials in different quadrants of the mouth.

Participants needed: 40
Trial details
Age: 4-9Biological sex: AllType: InterventionalSponsor: Universidad Autonoma de Baja CaliforniaUpdated: Jul 29, 2025Locations: 1
Eligibility criteria

Children aged 4 to 9 years with at least 2 primary molars affected by deep occlu... [+6]

Children with systemic diseases or medical conditions affecting oral health. [+5]

Status: Not yet recruiting

Orthodontic Treatment on Oral Microbiota and Salivary Proteins

Study on the changes in oral microbiota during orthodontic treatment in patients aged 8-18 years. Orthodontic patients treated at Stomatology Hospital of Xi'an Jiaotong University from March 2025 to March 2027 will be recruited. Prior to orthodontic treatment, routine preoperative examinations will be conducted, informed consent forms will be signed, baseline oral conditions will be recorded, and oral and psychological-related questionnaires will be completed. Patients will be informed of the need for regular oral hygiene check-ups, caries risk assessments will be performed, and plaque, saliva, and intraoral photographs will be collected. During orthodontic treatment, plaque samples will be collected every 3 months, and saliva samples will be collected every 6 months until the treatment is completed to evaluate the changes in oral microbiota throughout the orthodontic process.

Participants needed: 150
Trial details
Age: 6-18Biological sex: AllType: ObservationalSponsor: Xi'an Jiaotong UniversityUpdated: Jun 4, 2025Duration: 2 Years
Eligibility criteria

No carries and White spot [+4]

Antibiotic use in the past three months [+3]

Status: Not yet recruiting

Performance of Bioactive Low Viscosity Composite in Deep Marginal Elevation Restorations

The goal of this study is to evaluate the clinical, radiographic and periodontal performance of bioactive Giomer Shofu Flow Plus X F03 compared to nanohybrid resin composite restoration in deep subgingival proximal cavities over a period of 12 months.

Participants needed: 50
Trial details
Age: 20-50Biological sex: AllType: InterventionalSponsor: Future University in EgyptUpdated: Mar 21, 2025
Eligibility criteria

Adults patients (20-50) [+3]

Patients with known allergic or adverse reaction to the tested materials. [+6]

Status: Not yet recruiting

Effect of Caries Conceptualizing and Residential University Life

The study aims to detect the conceptualization of dental caries among dental student and compare the caries prevalence in residential and non residential dental student

Participants needed: 303
Trial details
Age: 20-22Biological sex: AllType: ObservationalSponsor: Sara Ibrahim Ahmed HediaUpdated: Sep 19, 2024
Eligibility criteria

Students already taught a dental cariology in 4th year of university. [+3]

First, second-, and third-year students. [+1]

Status: Not yet recruiting

Partial Caries Removal in Permanent Molars Restored Using Giomer

Dental manufacturers\' constant tweaks and improvements to composite compositions have resulted in a wider spectrum of restorative materials with positive long-term clinical performance. For example, the creation of bioactive giomer material with proven continuous multi-ion release has been beneficial in avoiding demineralization and imparting acid resistance to enamel and dentin.

Participants needed: 122
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: NewGiza UniversityUpdated: Sep 19, 2024
Eligibility criteria

18 -35 years. [+6]

known allergic reaction to resinous materials. [+8]