Coronary Flow During Rapid Heart Rates

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorImperial College London

About this trial

The goal of this observational study is to learn about the factors which determine how well ventricular tachycardia (VT) is tolerated. The main questions it aims to answer are:

1. What impact does coronary artery disease have on the ability for a patient to tolerate VT? 2. Does treatment of coronary artery disease with stents improve the tolerability of VT?

Participants who are undergoing a clinically indicated coronary angiogram or coronary angioplasty procedure will have measurements of blood pressure, coronary pressure and coronary flow made during pacing at a range of heart rates.

Eligibility criteria

Qualifiers

Able to give valid consent

Referred for coronary angiography or coronary angioplasty

Suitable for percutaneous physiological interrogation and PCI when clinically indicated

Disqualifiers

Unable to give valid consent

Pregnant or breastfeeding women

Unstable coronary artery disease (acute coronary syndrome)

Severe multivessel coronary artery disease suitable for coronary artery bypass grafting

Trial design

Treatments tested in this trial

  • Pressure and flow measurement during simulated VT

Treatment groups

70 Participants
are divided into 4 treatment groups

Sponsors and collaborators