Cumulative Live Birth Rates in Dual Ovarian Stimulation Versus Two Antagonist Stimulations in Poor Ovarian Responders

ConditionInfertility
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age20-44
SponsorShanghai First Maternity and Infant Hospital

About this trial

To compare the difference in cumulative live birth rates between dual ovarian stimulation and two antagonist stimulations in poor ovarian responders.

Eligibility criteria

Qualifiers

Women with POR were defined with adjusted Bologna criteria, at least two of the three following criteria: advanced maternal age (40 years); 3 oocytes in previous IVF; and antral follicle count (AFC) 5 and/or anti-Mu¨llerian hormone (AMH) 1.1 ng/ml (this criterion was mandatory)

Aged from 20 to 44 years

Body mass index (BMI) from 19 to 32 kg/m2

No more than two previous IVF cycles were recruited

Disqualifiers

Amenorrhoea

Follicle stimulating hormone (FSH) 20 IU/L or AFC 1

Women with a partner with an extremely severe sperm anomaly or sperm donor use

Trial design

Treatments tested in this trial

  • duostim vs. two antagonist ovarian stimulations

Treatment groups

260 Participants
are divided into 2 treatment groups

Locations

This trial has no locations