Dexamethasone Versus Magnesium Sulphate as an Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Plane Block for Postoperative Analgesia in Elective Caesarean Section Under Spinal Anesthesia

ConditionsDexamethasone Magnesium Sulphate Adjuvant Ultrasound Erector Spinae Plane Block Postoperative Analgesia Cesarean Section Spinal Anesthesia

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-35

SponsorCairo University

About this trial

This study aims to compare the efficacy of adding dexamethasone and magnesium sulfate as an adjuvant to bupivacaine in bilateral erector spinae block in postoperative pain control in patients undergoing caesarean section under spinal anesthesia.

Eligibility criteria

Qualifiers

Age from 18 to 35 years.

Full-term, singleton, pregnant women.

American Society of Anesthesiologists (ASA) physical status II.

Scheduled for elective cesarean delivery under spinal anesthesia.

Disqualifiers

Refusal of the patient.

Emergency caesarean sections.

Patients having chronic diseases as asthma, cardiovascular disorders (Significant arrhythmias, Severe Valvular diseases, congenital heart diseases, ischemic heart disease, cardiomyopathy, deep venous thrombosis ,and pulmonary embolism)

Renal impairment (Creatinine level ≥ 2mg/dl, urea ≥ 25mg/dL), liver impairment [Alanine aminotransferase (ALT) < 45 U/L, Aspartate aminotransferase (AST) < 45 U/L].

Trial design

Treatments tested in this trial

Bupivacaine
Dexamethasone
Magnesium sulphate

Treatment groups

150 Participants

are divided into 3 treatment groups

Sponsors and collaborators

Cairo University

Lead sponsor

Source ClinicalTrials.gov