Diagnostic Performance of the Mitral Annulus Velocity Variation Measured by Tissue Doppler to Evaluate the Fluid Responsiveness During the Initial Management of Shock in Patients Admitted to the Emergency Department

ConditionShock
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Nīmes

About this trial

Assessing the response to vascular filling in shock is a challenge in emergency medicine.

The mitral annulus velocity measured by tissue Doppler (E') has recently been characterized as sensitive to the preload conditions of a patient.

The investigators hypothesize that the E' variation (∆E') before and after fluid filling allows us to assess the response to vascular filling. The investigators hypothesize that the ∆E' has a good diagnostic performance to establish whether a patient is responsive to fluid filling, defined by an area under the ROC curve greater than 0.75.

Eligibility criteria

Qualifiers

Patient has been informed of the study and does not refuse to participate.

Patient is at least ≥ 18 years of age.

The patient must be beneficiary of a health insurance plan.

Patient has shock with a mean blood pressure less than 65 mmHg (<)

Disqualifiers

The patient has already received 2 vascular fillings since the beginning of his management

The patient is in shock and has a contraindication to vascular filling : shock of a cardiogenic or obstructive nature

The patient has an intracranial pathology requiring maintain a MAP ≥ 80 mmHg

The patient is intubated or on Non-Invasive Ventilation before the vascular filling

Trial design

Treatments tested in this trial

  • Cardiac ultrasonography

Treatment groups

187 Participants
are divided into 1 treatment group