Dilute Epinephrine vs Tourniquet for Visualization in Ankle Arthroscopy: A RCT

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-65
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

About this trial

This multicenter, prospective randomized controlled trial investigates the effect of dilute epinephrine irrigation versus tourniquet use on visual field clarity (VFC) during ankle arthroscopy. Patients are randomized into an epinephrine group (normal saline with 1 mL of 1:1000 epinephrine per 3 L bag; tourniquet placed but not inflated unless needed) or a standard tourniquet group. The primary outcome is arthroscopic visual field clarity assessed using a 4-point Likert-style numeric rating scale. Secondary outcomes include postoperative pain intensity at 2 and 24 hours (VAS), and the incidence of hypotension, bradycardia, and cardiovascular adverse events.

Eligibility criteria

Qualifiers

Able to understand the procedures and methods of the clinical trial

voluntarily provide written informed consent

Aged from 15 to 65 years old , regardless of sex

Diagnosed with a condition requiring ankle surgery

Disqualifiers

Patients who decline to participate in the study

Known history of heart disease (e.g., coronary artery disease, cardiac conduction abnormalities), diabetes, or asthma

Poorly controlled hypertension

Age under 15 years or above 65 years old

Trial design

Treatments tested in this trial

  • Epinephrine group
  • Tourniquet group

Treatment groups

88 Participants
are divided into 2 treatment groups

Locations

This trial has no locations