DNA Methylation and the Increased Risk of Cervical Cancer Development
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age15-50
SponsorZhujiang Hospital
About this trial
This study aims to investigate the correlation between reproductive tract microbiota and DNA methylation in cervical epithelial cells, as well as its impact on the development of cervical cancer, through a paired case-control clinical study
Eligibility criteria
Qualifiers
Aged 18-50 years old, with a history of sexual activity
HPV and TCT tests are performed concurrently in the gynecology clinic
Those with abnormal HPV and TCT test results undergo tissue pathological testing
Disqualifiers
Pregnant or breastfeeding
Patients with immunological disorders or severe autoimmune diseases, such as AIDS, SLE
Those who have had organ transplants or are currently using immunosuppressive agents
Use of vaginal douching within 48 hours before sample collection
Trial design
Treatments tested in this trial
- Reproductive tract microbiota
Treatment groups
2,000 Participants
are divided into 4 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov