This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant rehabilitation. Participants will be randomized 1:1 to immediate implant placement at the time of tooth extraction or to delayed implant placement after approximately 16 weeks of healing following extraction and ridge preservation as indicated. The primary endpoint is oral health-related quality of life assessed longitudinally using the OHIP-14 questionnaire and analyzed as the model-based mean score averaged across the active treatment phase from baseline through definitive crown delivery. Secondary outcomes include workflow-related patient experience, chairside time, number of visits, postoperative pain, buccal contour changes based on intraoral scan-derived volumetric analysis, radiographic marginal bone level changes, implant survival, clinical peri-implant parameters, technical complications, esthetic outcomes, accuracy of guided implant placement, and clinician-reported workflow outcomes.
Adults aged 18 years or older.
Indication for single implant therapy in a posterior premolar or molar extraction site.
Good oral hygiene with FMPS ≤20%.
Controlled periodontitis according to protocol definition.
• Known or suspected poor compliance, alcohol abuse, or substance abuse.
Systemic or local contraindications to implant surgery.
History of head/neck radiotherapy or recent malignancy within 5 years.
Use of medications affecting bone metabolism.
Heinrich-Heine University, Duesseldorf
Lead sponsor
The University of Hong Kong
Collaborator
ITI International Team for Implantology, Switzerland
Collaborator