Early Intra-aortic Balloon Pump Use After Venoarterial Extracorporeal Membrane Oxygenation
ConditionECMO
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBeijing Anzhen Hospital
About this trial
The goal of this multicenter, randomized trial is to compare early early left ventricular unloading by Intra-aortic Balloon Pump (IABP) versus conventional approach in patients with cardiogenic shock (CS) undergoing venoarterial extracorporeal membrane oxygenation (VA-ECMO). The main question it aims to answer is :
• If left ventricular unloading by IABP as compared with the conventional approach will improve the outcomes in patients undergoing VA-ECMO.
Eligibility criteria
Qualifiers
Age of ≥18
Cardiogenic shock(defined as a systolic blood pressure of less than 90 mm Hg for more than 30 minutes or the initiation of catecholamines to maintain a systolic pressure of more than 90 mm Hg, an arterial lactate level of more than 3 mmol per liter, and signs of impaired organ perfusion)
Successful implantation of VA-ECMO
Informed consent
Disqualifiers
SCAI shock stage A or B
Presence of moderate to severe aortic insufficiency or aortic dissection
Severe peripheral vascular disease
Post-cardiotomy cardiogenic shock(non-CABG procedure) or bridging to cardiac procedure(heart transplantation or LVAD).
Trial design
Treatments tested in this trial
- Early IABP use
- Conventional approach
Treatment groups
358 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov