Early Neuroprognostication After OHCA
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorLund University
About this trial
This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier than the 72 h time-point recommended by guidelines today.
Eligibility criteria
Qualifiers
a minimum of 20 minutes without chest compressions
Unconsciousness defined as not being able to obey verbal commands (FOUR-score motor response of <4) or being intubated and sedated because of agitation after sustained ROSC
Eligible for intensive care without restrictions or limitations
Inclusion within 4 hours of ROSC
Disqualifiers
On ECMO prior to randomisation
Pregnancy
Suspected or confirmed intracranial hemorrhage
Previously randomised in the STEPCARE trial
Trial design
Treatments tested in this trial
- Early neurological prognostication with biomarkers, EEG and CT
Treatment groups
No treatment groups listed
Sponsors and collaborators
Lund University
Lead sponsor
Helsingborgs Hospital
Collaborator
University of Helsinki
Collaborator
Skane University Hospital
Collaborator
Charite University, Berlin, Germany
Collaborator
Source ClinicalTrials.gov