To learn if topical capsaicin can help relieve pain from CIPN and improve gait (the pattern of walking) in patients.
Participants diagnosed with pain of the lower extremity from chronic (>90 days duration) CIPN (due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds), seen at MD Anderson Cancer Center
Participants reporting baseline pain ≥ 4 (0-10 scale, NRS)
Participants age 18+
Participants who have completed chemotherapy within the last year at the time of enrollment.
Participants with cognitive dysfunction
Participants with recent history (<6 months) of drug or alcohol abuse
Participants with open skin lesion or undergoing antibiotic therapy for local for systemic infection
Participants with allergies to capsaicin or adhesives
M.D. Anderson Cancer Center
Lead sponsor
Averitas Pharma, Inc.
Collaborator