Intracanal Dexamethasone Extrusion and Postoperative Endodontic Pain
Trial statusNot yet recruiting
Trial phaseEarly Phase 1
Trial typeInterventional
Biological sexAll
Age18-70
SponsorUniversity of Jordan
About this trial
The aim of this research is to assess the effect of intentionally extruding a corticosteroid intracanal solution into the periapical tissues on the postoperative pain after root canal treatment in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis (SIP/SAP). The main question it aims to answer: Is there an analgesic effect of extruding an intracanal solution of DXA into the periapical tissues in patients diagnosed with SIP/SAP? Researchers will compare dexamethasone to a placebo to see if the extrusion dexamethasone works in reducing post-endodontic treatment pain.
Eligibility criteria
Qualifiers
A diagnosis of irreversible pulpits with symptomatic apical periodontitis
Adult patients (aged 18 - 70)
Healthy patients or those with a well-controlled disease (ASA I & II)
Disqualifiers
A diagnosis of necrotic pulp, or normal apical tissues
Patients with a severe systemic disease (ASA III or higher)
Patients who received analgesics12 hours before presentation
Previously treated/initiated Endodontics treatment on the same tooth
Trial design
Treatments tested in this trial
- Dexamethasone
- Placebo
Treatment groups
80 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov