About this trial
In modern anesthesia practice, anesthesiologists often need to choose a combination of multiple drugs according to the specific conditions and surgical needs of patients, which can not only achieve more fine anesthesia management, but also improve perioperative safety and patient comfort. In clinical practice, anesthesiologists will use etomidate combined with a small dose of remimazolam for anesthesia induction to obtain more stable hemodynamics, prevent intraoperative awareness, and relieve anxiety.However, what is the best dose ratio of etomidate combined with remimazolam, the current literature does not give clear indicators.
Eligibility criteria
Qualifiers
Both sexes
aged 18-60 yr
ASA physical status I-II
BIM: 18-28kg/m²
Disqualifiers
allergic to remimazolam and etomidate
in pregnancy or lactation
serious cardiovascular diseases, long-term alcoholism
used sedative drugs or opioids within 24 hours
Trial design
Treatments tested in this trial
- Etomidate
- Remimazolam
- Remimazolam-etomidate