Repeated CBD Administration and Cannabis Outcomes

Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or alcohol that would require medical management,

Clinically significant acute medical problem (e.g., infection) or chronic medical problem requiring daily medication or ongoing medical care (e.g., hypertension, cardiovascular disease, diabetes, respiratory disorders [e.g., asthma, COPD]),

Current or past history of major psychiatric disorder that would limit ability to participate in the study,

Use of cannabis exclusively for medical reasons (no recreational use reported),