Health Trials

Abuse Liability

2

Review clinical trials related to Abuse Liability. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Repeated CBD Administration and Cannabis Outcomes

This outpatient study examines how cannabidiol (CBD) affects the behavioral and pain-relieving effects of cannabis.

Participants needed: 23
Trial details
Phase: Early Phase 1Age: 18-55Biological sex: AllType: InterventionalSponsor: Hannah HarrisUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

English-speaking, literate adults, [+8]

Physiologic drug dependence on opioids, benzodiazepines, barbiturates, and/or al... [+10]

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Status: Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

The overarching goal of this double-blind, placebo-controlled, crossover study is to characterize the pharmacokinetic (PK) and pharmacodynamic (PD) effects of the main analgesic and psychoactive constituent of cannabis, delta-9 tetrahydrocannabinol (THC), among older adults - the fastest growing population of cannabis consumers, and the most likely age cohort to use cannabinoids to relieve pain. This protocol includes two sub-studies, each randomizing 20 men and women aged 65 years or older to receive two administration routes of THC; oral administration and vaporized administration.

Participants needed: 20
Trial details
Phase: Early Phase 1Age: 65+Biological sex: AllType: InterventionalSponsor: Yale UniversityUpdated: Feb 23, 2026Locations: 1
Eligibility criteria

Healthy male and female participants aged 65 ≥ years old [+2]

Meeting DSM-5 criteria for psychiatric/substance use disorders (SUD) other than... [+16]

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