the Objectives of this clinical trial is :
1. To determine the effect of Cold Application for preventing of chemotherapy-Induced oral mucositis in cancer patients. 2. To examine the effect of artificial saliva for preventing of chemotherapy-Induced oral mucositis in cancer patients. 3. To compare between the effect of artificial saliva and cold application for preventing of chemotherapy-Induced oral mucositis in cancer patients. 4. To find out the differences between the effect of artificial saliva and cold application based on patient demographics and clinical data.
Patients who undergo chemotherapy.
Patients who do not have oral mucositis.
Patients who are aged 18 years and older.
Patients who are male or female.
Patients who was refused to participate in the study.
Patients who was not undergoing chemotherapy.
Patients how was undergoing chemo-radiotherapy.
Patients who selected for pilot study.