Effect of Ginkgo Biloba Extract on Cognitive Function in Acute Ischemic Stroke
ConditionAcute Ischemic Stroke
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorYi Yang
About this trial
The purpose of this study is to determine the effect of ginkgo biloba extract on cognitive function in acute ischemic stroke.
Eligibility criteria
Qualifiers
Patients with a definitive clinical diagnosis of acute ischemic stroke;
Age≥18 years, regardless of sex；
Primary education level or higher; baseline MoCA score of 10-25 points;
Able to complete cognitive scale scoring;
Disqualifiers
Transient ischemic attack；
Patients who received emergency reperfusion therapy (including intravenous thrombolysis and endovascular thrombectomy) at onset;
Combined with other neurological diseases, such as neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia), optic neuritis, epilepsy, central nervous system infections (e.g., AIDS and syphilis), traumatic brain injury dementia, etc；
Currently using psychoactive medications (e.g., antidepressants) or anti-epileptic drugs, or if the time since their last use of these medications was less than 5 half-lives (per the pharmacokinetics of each specific medication; for drugs with unknown half-lives, a 1 month washout period was required)；
Trial design
Treatments tested in this trial
- Ginkgo Biloba Extract
Treatment groups
356 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Yi Yang
Lead sponsor
The First Hospital of Jilin University
Sponsor institution
Source ClinicalTrials.gov