Effect of Nutritional Support and Early Rehabilitation on Sepsis

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorJinling Hospital, China

About this trial

Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a short time.This pathology frequently leads to prolonged hospitalization and mechanical ventilation, increased mortality, and reduced quality of survival.It is uncertainty whether sepsis patients in ICU can benefit from high protein intake combined with early exercise. Even though the combination has been shown to be beneficial in other populations.In the present study, the investigator will evaluate the effects of a combination of high protein targets combined with early rehabilitation in sepsis patients in ICU.

Eligibility criteria

Qualifiers

Patients with sepsis

Patients aged 18-70 years

Time of admission ≤48 h

Non-terminal condition

Disqualifiers

None

Trial design

Treatments tested in this trial

  • high protein
  • rehabilitation
  • standard protein

Treatment groups

1,600 Participants
are divided into 4 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Jinling Hospital, China

Lead sponsor

The First Affiliated Hospital of Soochow University

Sponsor institution

The First Affiliated Hospital of Soochow University

Collaborator