About this trial
The goal of this observational study is to learn about the association between vasopressor exposure levels and outcomes in adults with cardiogenic shock receiving VA-ECMO. The main question it aims to answer is:
Does reduced exposure to vasopressors lower the 30-day mortality in patients with cardiogenic shock when receiving ECMO support? Participants who are receiving ECMO support for cardiogenic shock as part of their regular medical care will have their data collected, including information about their vasopressor use and mortality outcomes, over the course of the study.
Eligibility criteria
Qualifiers
Adults (≥18 years) with cardiogenic shock requiring VA-ECMO support.
First-time ECMO initiation.
Venoarterial ECMO (VA-ECMO) as the initial mode.
Disqualifiers
Age <18 years.
Severe pulmonary hypertension.
Vasopressor use for non-shock indications (e.g., bleeding, post-cardiopulmonary bypass vasoplegia).
Severe missing data.
Trial design
Treatments tested in this trial
- Vasopressor Exposure Levels
Treatment groups
Sponsors and collaborators
Xiaotong Hou
Lead sponsor
Beijing Anzhen Hospital
Sponsor institution