Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorXiaotong Hou

About this trial

The goal of this observational study is to learn about the association between vasopressor exposure levels and outcomes in adults with cardiogenic shock receiving VA-ECMO. The main question it aims to answer is:

Does reduced exposure to vasopressors lower the 30-day mortality in patients with cardiogenic shock when receiving ECMO support? Participants who are receiving ECMO support for cardiogenic shock as part of their regular medical care will have their data collected, including information about their vasopressor use and mortality outcomes, over the course of the study.

Eligibility criteria

Qualifiers

Adults (≥18 years) with cardiogenic shock requiring VA-ECMO support.

First-time ECMO initiation.

Venoarterial ECMO (VA-ECMO) as the initial mode.

Disqualifiers

Age <18 years.

Severe pulmonary hypertension.

Vasopressor use for non-shock indications (e.g., bleeding, post-cardiopulmonary bypass vasoplegia).

Severe missing data.

Trial design

Treatments tested in this trial

  • Vasopressor Exposure Levels

Treatment groups

534 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Xiaotong Hou

Lead sponsor

Beijing Anzhen Hospital

Sponsor institution