Effect of Sarcopenia and Frailty on Rocuronium Pharmacodynamics in Geriatric Patients
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65-80
SponsorKonya Meram State Hospital
This prospective observational study aims to evaluate whether sarcopenia and frailty affect the pharmacodynamic profile of rocuronium in geriatric patients undergoing elective surgery under general anesthesia.
Scheduled to undergo elective surgery under general anesthesia requiring endotracheal intubation
Planned use of rocuronium for neuromuscular blockade
Quantitative neuromuscular monitoring planned during anesthesia
American Society of Anesthesiologists physical status I-III
Emergency surgery
Known neuromuscular disease
History of allergy or contraindication to rocuronium, sugammadex
Severe hepatic insufficiency