Effect of Sevoflurane on Sweat Threshold in Children of Different Ages
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 12
SponsorSecond Affiliated Hospital of Wenzhou Medical University
About this trial
Hypothermia is a common complication in pediatric anesthesia. Hypothermia will prolong the recovery time of anesthesia, and may also lead to increased oxygen consumption, prolonged blood coagulation time, and affect the metabolism of anesthetic drugs and postoperative immune function. Sevoflurane is the most commonly used inhaled anesthetic in children. This study explored the effect of sevoflurane on the sweat threshold of pediatric patients and analyzed the characteristics of body temperature regulation in children of different ages under anesthesia, which will help to understand the mechanism of body temperature regulation in children under anesthesia, and also provide a scientific basis for clinical anesthesia temperature management.
Eligibility criteria
Qualifiers
Age: 0-12 years old;
American Society of Anesthesiologists physical status I or II;
Weight within the normal range and body-mass index (BMI) for age between the 25th and 85th percentiles;
scheduled elective lower-body surgery under general anesthesia, expected to last at least 1 hour.
Disqualifiers
The guardian of the child refused to participate in the study;
Operations involving extensive incisions, such as massive debridement or other operations requiring removal of large amounts of tissue;
Contraindications to esophageal temperature probe insertion (e.g., esophageal varices, congenital anomalies);
Thyroid dysfunction or autonomic dysfunction;
Trial design
Treatments tested in this trial
- temperature monitoring
- Sevoflurane
Treatment groups
100 Participants
are divided into 5 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov