Effects of Ketone Ester Consumption on Exercise Tolerance and Cardiac Function
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorOhio State University
About this trial
This study is being done to evaluate how a ketone ester (KE) supplement affects heart function and health in people with diabetes compared to a placebo supplement (made with standard food ingredients that do not contain ketone esters).
Eligibility criteria
Qualifiers
Age ≥ 18 years old and ≤ 80 years old
Type II Diabetes Mellitus
Stable medical therapy for at least 1 months as determined by the treating physician (no plan to change between the two testing sessions)
Dose of oral diuretics changes allowed, but must be stable for 1 week prior to randomization
Disqualifiers
Women who are pregnant, current breast-feeding, or have intention to become pregnant while in the trial
Known allergy or sensitivity to Gadolinium based contrast agents
Implanted pacemaker, cardioverter defibrillator, cardiac resynchronization therapy, left ventricular assist device
Other metallic implants/aneurysm clips that are contraindicated in MRI
Trial design
Treatments tested in this trial
- Ketone Ester Acute
- Placebo Acute
Treatment groups
30 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov