Efficacy and Safety Research of Cold Snare Polypectomy and Hot Snare Polypectomy in the Treatment of 4-9 mm Diameter Colorectal 0-Isp and 0-Ip Polyps: a Prospective, Multicenter, Randomized Controlled Study(FAST -REST Study)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorRuijin Hospital

About this trial

This study will evaluate the efficacy and safety of cold snare polypectomy(CSP) and hot snare polypectomy(HSP) in the treatment of colorectal 4-9mm 0-Isp and 0-Ip polyps, and compare the complete resection rate, postoperative late bleeding rate, intraoperative bleeding rate, en bloc resection rate, operation time and the number of metal clips used. The conclusion of this study will help clinical doctor develop more effective resection strategies for colorectal 0-Isp and 0-Ip polyps, and provide more effective treatment for patients.

Eligibility criteria

Qualifiers

Age: 18-80 years old, male or female

At least one polyp with size of 4-9 mm 0-Isp or 0-Ip is found during colonoscopy

Voluntarily sign informed consent for endoscopic treatment

Disqualifiers

Boston Bowel Preparation Scale<6 points.

Patients who receive antiplatelet/anticoagulant therapy within 5 days before polypectomy.

Participants with a contraindication to colonoscopy and polypectomy.

Patients with inflammatory bowel disease or gastrointestinal polyposis.

Trial design

Treatments tested in this trial

  • cold snare polypectomy
  • hot snare polypectomy

Treatment groups

982 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Ruijin Hospital

Lead sponsor

Jinshan Hospital Fudan University

Collaborator

Second Affiliated Hospital of Soochow University

Collaborator

The Third People's Hospital of Yunnan Province

Collaborator

People's Hospital Mojiang

Collaborator

Shanghai Yueyang Integrated Medicine Hospital

Collaborator

Huadong Hospital

Collaborator