Endovascular Revascularization for Chronic Carotid Artery Occlusion Trial
ConditionCarotid Occlusion
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorNational Taiwan University Hospital
About this trial
Revascularization for carotid artery occlusion (CAO) remained controversial, there is no prospective randomized control trial (RCT) regarding carotid artery stenting (CAS) in CAO patients. The investigators conduct a prospective study composed of clinical registry arm and RCT arm. The main purpose of the study is investigate neurocognitive function at 3 months and thereafter up to 12 months.
Eligibility criteria
Qualifiers
Patient age 20 years or older
Abnormal cerebral perfusion by CTP or MRI
No medical history of stroke or transient ischemic attack (TIA) ipsilateral to the carotid occlusion within 90 days of randomization
Women must not be of childbearing potential or, if of childbearing potential, have a negative pregnancy test prior to randomization.
Disqualifiers
Patient has acute stroke within 90 days,
Intolerance or allergic reaction to a study medication without a suitable management alternative.
Patient is expected to have the ADP antagonist therapy interruption within 3 months after the procedure.
GI hemorrhage within 1 month prior to enrollment that would preclude antiplatelet therapy
Trial design
Treatments tested in this trial
- Endovascular revascularization
Treatment groups
200 Participants
are divided into 4 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov