European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity of Padova

About this trial

Anomalous aortic origin of a coronary artery (AAOCA) is a group of rare congenital heart defects with various clinical presentations. The lifetime-risk of an individual living with AAOCA is unknown, and data from multicentre registries are urgently needed to adapt current recommendations and guide optimal patient management. The European Registry for AAOCA (EURO-AAOCA) aims to assess differences with regard to AAOCA management between centres.

Eligibility criteria

Qualifiers

All patients with a diagnosis of AAOCA (either referred to surgery or to medical follow-up )

Disqualifiers

isolated high-coronary take-off (≥ 5mm above sino-tubular junction), anomalous origin of a circumflex from the right coronary artery, anomalous course with a normal origin, and association to major congenital heart disease (i.e. Tetralogy of Fallot, transposition of the great arteries, anomalous origin of a coronary from the pulmonary artery).

Trial design

Treatments tested in this trial

  • unroofing or other surgery if needed

Treatment groups

500 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Padova

Lead sponsor

IRCCS Policlinico S. Donato

Collaborator

Mitera Children's Hospital, Athens Heart Surgery Institute, Greece

Collaborator

Ospedale Civile Ca' Foncello

Collaborator

University Hospital, Ghent

Collaborator

Guy's and St Thomas' NHS Foundation Trust

Collaborator

Azienda Ospedaliera Universitaria Integrata Verona

Collaborator

University Medical Center Groningen

Collaborator

Hospital Universitario La Paz

Collaborator

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Collaborator

Insel Gruppe AG, University Hospital Bern

Collaborator

Azienda Ospedaliero-Universitaria di Parma

Collaborator