About this trial
The goal of this clinical trial is to learn whether high-dose multimodal prehabilitation, delivered either in person or remotely with coaching and web application support, is feasible and acceptable for women preparing for ovarian cancer surgery. It will also examine which delivery model patients prefer and the factors influencing patient preferences.
The main questions ADAPT-OC aims to answer are:
1. Can participants achieve the prescribed aerobic exercise target of at least 10 MET-hours per week before surgery? 2. Do patients prefer in-person prehabilitation, remote prehabilitation, or education-only care, and what factors influence that preference?
The researchers will compare in-person prehabilitation, remote prehabilitation, and education-only care to see which delivery approach is most feasible, acceptable, and practical for patients with suspected ovarian cancer.
Participants will:
* Choose their preferred study group, or be randomly assigned if they have no preference * Complete physical assessments, questionnaires, and interviews at baseline, 1-3 days before surgery, and 4 weeks after surgery * If assigned to a prehabilitation group, complete aerobic exercise, protein supplementation, and daily breathing exercises before surgery * Attend weekly coaching sessions with a trained prehabilitation coach * Use the KingstonPrehab web application to track exercise, nutrition, breathing practice, and progress toward activity goals
Eligibility criteria
Qualifiers
Female
Aged ≥18 years
Scheduled for cytoreductive surgery for an ovarian mass suspected or confirmed of cancer
Surgery planned ≥3 weeks from time of booking
Disqualifiers
Pregnancy
Surgery scheduled <3 weeks from booking
Receiving neoadjuvant chemotherapy
Positive contraindications to exercise on the CSEP Get Active Questionnaire
Trial design
Treatments tested in this trial
- Multimodal Prehabilitation Program
- Educational Materials
Treatment groups
Sponsors and collaborators
Jordan Leitch
Lead sponsor
Queen's University
Sponsor institution
Kingston Health Sciences Centre
Collaborator
Queen's University
Collaborator