Evaluating the Feasibility of Prehabilitation Delivery Models for Patients Preparing for Ovarian Cancer Surgery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18+
SponsorJordan Leitch

About this trial

The goal of this clinical trial is to learn whether high-dose multimodal prehabilitation, delivered either in person or remotely with coaching and web application support, is feasible and acceptable for women preparing for ovarian cancer surgery. It will also examine which delivery model patients prefer and the factors influencing patient preferences.

The main questions ADAPT-OC aims to answer are:

1. Can participants achieve the prescribed aerobic exercise target of at least 10 MET-hours per week before surgery? 2. Do patients prefer in-person prehabilitation, remote prehabilitation, or education-only care, and what factors influence that preference?

The researchers will compare in-person prehabilitation, remote prehabilitation, and education-only care to see which delivery approach is most feasible, acceptable, and practical for patients with suspected ovarian cancer.

Participants will:

* Choose their preferred study group, or be randomly assigned if they have no preference * Complete physical assessments, questionnaires, and interviews at baseline, 1-3 days before surgery, and 4 weeks after surgery * If assigned to a prehabilitation group, complete aerobic exercise, protein supplementation, and daily breathing exercises before surgery * Attend weekly coaching sessions with a trained prehabilitation coach * Use the KingstonPrehab web application to track exercise, nutrition, breathing practice, and progress toward activity goals

Eligibility criteria

Qualifiers

Female

Aged ≥18 years

Scheduled for cytoreductive surgery for an ovarian mass suspected or confirmed of cancer

Surgery planned ≥3 weeks from time of booking

Disqualifiers

Pregnancy

Surgery scheduled <3 weeks from booking

Receiving neoadjuvant chemotherapy

Positive contraindications to exercise on the CSEP Get Active Questionnaire

Trial design

Treatments tested in this trial

  • Multimodal Prehabilitation Program
  • Educational Materials

Treatment groups

36 Participants
are divided into 3 treatment groups

Sponsors and collaborators

Jordan Leitch

Lead sponsor

Queen's University

Sponsor institution

Kingston Health Sciences Centre

Collaborator

Queen's University

Collaborator