About this trial
This study evaluates the use of Concentrated Growth Factor (CGF) plugs-a third-generation healing material made from the patient's own blood-to improve recovery after simple tooth extractions. CGF contains a dense matrix of growth factors and regenerative cells designed to enhance wound healing and tissue regeneration.
Participants requiring a single, non-surgical tooth extraction will have a CGF plug placed into the empty socket immediately following the procedure. The researchers will then monitor two main factors:
* Post-operative Pain: Patients will record their pain levels on a scale of 0 to 10 at 1, 3, and 7 days after the extraction. * Bone Density: Using specialized imaging (CBCT), the researchers will measure how well the bone heals and fills the socket immediately after the procedure and again at 3 months.
The goal of this research is to determine if CGF plugs can effectively reduce patient discomfort and help preserve bone density, which is critical for future dental treatments like implants.
Eligibility criteria
Qualifiers
Systemically healthy patients (ASA I or II)
Age between 20 and 50 years
Require simple, non-surgical extraction of a single tooth
Presence of periapical radiolucency at the extraction site
Disqualifiers
• Systemic diseases (e.g., uncontrolled diabetes, bone metabolic disorders)
History of radiotherapy or chemotherapy
Use of medications affecting bone metabolism (e.g., bisphosphonates, chronic steroids)
Heavy smokers
Trial design
Treatments tested in this trial
- Concentrated Growth Factor (CGF) Plug