Phase 1 (started in July 2019):
Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete understanding on the development of CPHP is lacking. The study aims to identify clinically-relevant factors for CPHP that can be reliably assessed preoperatively.
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Phase 2 (anticipated start May 2022):
In addition to above factors, the association between heart rate variability (HRV) parameters, anxiety level, anticipated pain, and anticipated analgesia requirement with significant postoperative pain and CPHP will be investigated.
Age 21 to 80 years old
American Society of Anesthesiologists Physical Scale (ASA) I to III
Benign gynaecological indications for hysterectomy
Elective abdominal or laparoscopic hysterectomy
Vaginal hysterectomy
Uterine prolapse, endometriosis, malignant disease, or pelvic pain as main indication for surgery
History of drug dependence or recreational drug use
History of chronic pain syndrome