About this trial
This study aims to evaluate the efficiency of intermittent enteral nutrition versus continuous enteral nutrition to prevent from organ failures for patients at the acute phase of sepsis shock with mechanical ventilation in ICU.
Eligibility criteria
Qualifiers
Patient admitted in ICU for less than 48h, with invasive mechanical ventilation predicted for at least 48h, that can undergo nasogastric feeding for 7 days.
Patient under vasopressive drugs
Adult patients (age ≥ 18 years)
Informed person who has read and signed their consent
Disqualifiers
Contraindication to enteral nutrition and/or nasogastric tube insertion: esophageal varices and occlusive syndrome
Artificial enteral nutrition that cannot be initiated within 48 hours of intubation
Enteral nutrition ongoing for more than one hour at the time of inclusion
Need for exclusive or supplemental parenteral nutrition
Trial design
Treatments tested in this trial
- Intermittent enteral nutrition
Treatment groups
Sponsors and collaborators
University Hospital, Rouen
Lead sponsor
University Hospital, Lille
Collaborator
University Hospital, Caen
Collaborator
Amiens University Hospital
Collaborator
Centre Hospitalier Saint-Philibert, GHICL
Collaborator
Centre Hospitalier Intercommunal Elbeuf-Louviers-Val de Reuil
Collaborator
Groupe Hospitalier du Havre
Collaborator
Centre Hospitalier de Dieppe
Collaborator