Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorUniversity of Southern California

About this trial

The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exercise. This study aims to uncover how the different estrogen and progesterone concentrations present throughout the menstrual cycle effect perceived readiness to perform, perceptions of difficulty, and different recovery metrics.

Eligibility criteria

Qualifiers

18-35 years of age

BMI of 18.5-29.9 as a BMI below or above these cut points results in highly varied menstrual cycle lengths [15]

Not taking contraception or other types of medication that could influence reproductive status

Regular menstruation

Disqualifiers

Amenorrhea or oligomenorrhea

Perimenopausal or menopausal

Recreational or professional trail or downhill runner

On a form of contraception

Trial design

Treatments tested in this trial

  • Eccentric leg extension

Treatment groups

30 Participants
are divided into 3 treatment groups