Exercise Effects on Adipose Tissue Structure and Function
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-40
SponsorUniversity of Michigan
About this trial
Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.
Eligibility criteria
Qualifiers
Age: 18-40
Body Mass Index: 27-45 kg/m2
No regularly planned exercise/physical activity for at least 6 months
Women must have regularly occurring menses and must be premenopausal
Disqualifiers
Evidence/history of cardiovascular or metabolic disease
Medications known to affect lipid or glucose metabolism, or inflammation
Weight instability ≥ ± 6 pounds in the last 3 months
Tobacco or e-cigarette users
Trial design
Treatments tested in this trial
- Exercise
- No exercise
Treatment groups
46 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov