Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorSaint Petersburg State University, Russia
About this trial
PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.
Eligibility criteria
Qualifiers
A hospital that performs a minimum of 250 open heart interventions per year.
Consent from hospital physicians regarding the prophylactic use of fibrinolysis inhibitors (more than 95% of physicians involved in the treatment of adult patients (>18 years) agree to adhere to the strategy of using fibrinolysis inhibitors as prescribed by the study protocol).
Disqualifiers
Hospital does not meet inclusion criteria
Trial design
Treatments tested in this trial
- No routine fibrinolysis inhibitors after surgery
- Routine fibrinolysis inhibitors after surgery
Treatment groups
1,373 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov