Health Trials

Fibrinolysis Shutdown

2

Review clinical trials related to Fibrinolysis Shutdown. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Extended Perioperative Administration of Fibrinolysis Inhibitors After Cardiac Surgery

PRIORITY is a pragmatic, multi-center, cluster crossover trial that aims to evaluate whether implementing a policy of routine extended (intraoperative and 4 hour after transfer to ICU) use of fibrinolysis inhibitors leads to a decrease in post-operative blood transfusion compared to a policy that only involves intraoperative use.

Participants needed: 1,373
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Saint Petersburg State University, RussiaUpdated: Jan 27, 2025Locations: 2
Eligibility criteria

A hospital that performs a minimum of 250 open heart interventions per year. [+1]

Hospital does not meet inclusion criteria

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Status: Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure

Patients with coronavirus disease (COVID) and non-COVID acute respiratory failure (ARF) may be at an increased risk of thrombosis due to increased clot formation and decreased clot lysis. This two stage study aims to utilise bedside coagulation technology to detect patients at increased risk and guide tPA treatment to maximise efficacy and safety through a personalised approach.

Participants needed: 70
Trial details
Phase: Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: South West Sydney Local Health DistrictUpdated: Apr 17, 2024Locations: 1
Eligibility criteria

Acute respiratory failure of primary pulmonary infectious or extrapulmonary infe... [+4]

Platelet count <150 x 109/L or a reduction in platelet count of 50% or more in t... [+19]

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